RT article T1 Effect of handling on stress-induced hyperthermia in adult rabbits A1 Olivas, Irene A1 Villagra, Arantxa K1 Stress-induced hyperthermia K1 Benzodiazepine K1 L01 Animal husbandry K1 L70 Veterinary science and hygiene K1 Rabbits K1 Handling K1 Behaviour AB Animals perceive humans as a threat, therefore handling could cause stress reactions and fear inrabbits. Stress induced hyperthermia (SIH) is a physiological response produced when a stressful situationtakes place and is supposed to occur in rabbits. In this work, the SIH response is assessed when differentgroups of rabbits (young males, nulliparous does and multiparous does) are handled. A benzodiazepine(Midazolam®) was administered to half of the animals to assess handling response also under drug effects.Rectal temperature was not increased by handling in male rabbits and multiparous does, whereas nulliparousfemales showed presented SIH after 30 min of handling. In addition, Midazolam® has been revealed as usefulfor pharmacological validation of SIH after 25 min from injection. PB WRSA-UPV SN 1257-5011 YR 2013 FD 2013 LK http://hdl.handle.net/20.500.11939/7043 UL http://hdl.handle.net/20.500.11939/7043 LA en NO Olivas, I., & Villagrá, A. (2013). Effect of handling on stress-induced hyperthermia in adult rabbits. World Rabbit Science, 21(1), 41-44. DS MINDS@UW RD Feb 4, 2023