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dc.contributor.authorPenadés, José R.
dc.contributor.authorDonderis, Jorge
dc.contributor.authorGarcia-Caballer, Maria
dc.contributor.authorTormo-Mas, María A.
dc.contributor.authorMarina, Alberto
dc.date.accessioned2017-06-01T10:09:53Z
dc.date.available2017-06-01T10:09:53Z
dc.date.issued2013
dc.identifier.citationPenades, J.R., Donderis, J., Garcia-Caballer, M., Angeles Tormo-Mas, M., Marina, A. (2013). dUTPases, the unexplored family of signalling molecules. Current opinion in microbiology, 16(2), 163-170.
dc.identifier.issn1369-5274
dc.identifier.urihttp://hdl.handle.net/20.500.11939/4342
dc.description.abstractDeciphering the molecular mechanisms that control relevant cellular processes is of utmost importance to understand how viruses, prokaryotic and eukaryotic cells work. The diversity of living organisms suggests that there are novel regulators still to be discovered, which may uncover new regulatory paradigms. dUTPases (Duts) are assumed to be ubiquitous enzymes regulating cellular dUTP levels to prevent misincorporation of uracil into DNA. Recently however, Duts have been involved in the control of several relevant cellular processes, including transfer of mobile genetic elements, regulation of the immune system, autoimmunity or apoptosis, suggesting that they perform regulatory functions. This review aims at investigating the unexplored impact of Duts as novel signalling molecules.
dc.language.isoen
dc.titledUTPases, the unexplored family of signalling molecules
dc.typearticle
dc.authorAddressInstituto Valenciano de Investigaciones Agrarias (IVIA), Carretera CV-315, Km. 10’7, 46113 Moncada (Valencia), Españaes
dc.date.issuedFreeFormAPR 2013
dc.entidadIVIACentro de Tecnología Animal
dc.identifier.doi10.1016/j.mib.2013.02.005
dc.journal.abbreviatedTitleCurr.Opin.Microbiol.
dc.journal.issueNumber2
dc.journal.titleCurrent opinion in microbiology
dc.journal.volumeNumber16
dc.page.final170
dc.page.initial163
dc.rights.accessRightsopenAccess
dc.source.typeImpreso


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