RT article T1 Plum Pox Virus and Sharka Disease A1 García, Juan Antonio A1 Cambra, Mariano K1 Host range K1 Pathogenicity determinant K1 Potyviridae K1 Sharka K1 Virus diagnosis K1 Virus resistance K1 Virus vector K1 H20 Plant diseases K1 Plum pox virus K1 Potyviruses AB Sharka is a disease of fruiting, ornamental and wild Prunus species of great socio-economic relevance that has spread to most Prunus- growing nations. It is caused by Plum pox virus (PPV), a member of the genus Potyvirus. In recent years, there have been notable advances in our understanding of genome organization and expression, functions of gene products, and pathogenicity and host range determinants of PPV and other potyviruses. This knowledge is being applied to improve PPV detection and strain differentiation. In addition, the feasibility of engineering the PPV genome through cDNA cloning has opened the possibility of using PPV as a biotechnological tool. The combined application of classical breeding and genetic engineering techniques is yielding first results in the development of Prunus cultivars resistant to sharka disease. PB Global Science Books (GSB) SN 1749-6209 YR 2007 FD 2007 LK http://hdl.handle.net/20.500.11939/6496 UL http://hdl.handle.net/20.500.11939/6496 LA en NO García, J. A., & Cambra, M. (2007). Plum pox virus and sharka disease. Plant Viruses, 1(1), 69-79. DS MINDS@UW RD Jan 16, 2021