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dc.contributor.authorScorza, Ralph
dc.contributor.authorCallahan, Ann
dc.contributor.authorDardick, Chris
dc.contributor.authorRavelonandro, Michel
dc.contributor.authorPolak, Jaroslav
dc.contributor.authorMalinowski, Tadeusz
dc.contributor.authorZagrai, Ioan
dc.contributor.authorCambra, Mariano
dc.contributor.authorKamenova, Ivanka
dc.date.accessioned2017-06-01T10:10:18Z
dc.date.available2017-06-01T10:10:18Z
dc.date.issued2013
dc.identifier.citationScorza, Ralph, Callahan, Ann, Dardick, Chris, Ravelonandro, Michel, Polak, Jaroslav, Malinowski, Tadeusz, Zagrai, Ioan, Cambra, M., Kamenova, Ivanka (2013). Genetic engineering of Plum pox virus resistance: 'HoneySweet' plum-from concept to product. Plant Cell Tissue and Organ Culture, 115(1), 1-12.
dc.identifier.issn0167-6857
dc.identifier.urihttp://hdl.handle.net/20.500.11939/4504
dc.description.abstractSharka disease, caused by Plum pox virus (PPV) was first recorded in Bulgaria during the early twentieth century and since that first report, the disease has progressively spread throughout Europe and more recently to Asia, Africa, North and South America. Few PPV resistance genes have been found to naturally occur in Prunus and this has led to the investigation of biotech approaches to the development of resistance through genetic engineering (GE). A notable example of the utility of this approach is ‘HoneySweet’ plum. PPV protection in this case is based on RNA interference (RNAi) and resistance has been shown to be highly effective, stable, durable, and heritable as a dominant trait. Extensive testing and risk assessment of ‘HoneySweet’ in laboratory, greenhouse and in the field for over 20 years has demonstrated not only the effectiveness but also the safety of the technology. ‘HoneySweet’ has been cleared for cultivation in the USA. By the appropriate regulatory agencies. The development and regulatory approval of ‘HoneySweet’ demonstrate the ability of RNAi technology to contribute to the sustainability of stone fruit production in regions impacted by PPV. Although it has taken almost 100 years since the identification of sharka, we are now able to effectively protect stone fruit species against this disease through the application of GE.
dc.language.isoen
dc.titleGenetic engineering of Plum pox virus resistance: 'HoneySweet' plum-from concept to product
dc.typearticle
dc.authorAddressInstituto Valenciano de Investigaciones Agrarias (IVIA), Carretera CV-315, Km. 10’7, 46113 Moncada (Valencia), Españaes
dc.date.issuedFreeFormOCT 2013
dc.entidadIVIACentro de Protección Vegetal y Biotecnología
dc.identifier.doi10.1007/s11240-013-0339-6
dc.journal.issueNumber1
dc.journal.titlePlant Cell Tissue and Organ Culture
dc.journal.volumeNumber115
dc.page.final12
dc.page.initial1
dc.rights.accessRightsopenAccess
dc.source.typeImpreso


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